The physician Dr Hettinger erected the architecturally impressive building between 1899 and 1900 and ran a lung sanatorium in it from 1900. For financial reasons, he sold the sanatorium in 1905 to the "M. A. von Rothschild'sche Stiftung für lungenkranke Frauen" (M. A. von Rothschild Foundation for Women with Lung Disease), which Adelheid de Rothschild had founded on 7 April 1903 in memory of her father.
The Rothschild Sanatorium, which had been run according to orthodox standards since 15 November 1905 at the request of the founder, housed Jewish medical staff and had 48 spacious hospital rooms, common rooms, a synagogue, reading rooms and three lying-in halls at different altitudes. The foundation also owned a 22-hectare Jewish cemetery, acquired by Leo Maile on 15 May 1907. 28 of the 51 Jewish people who died in Nordrach between 1905 and 1941 found their final resting place there. On 29 September 1942, the last remaining Jewish people, including head physician Dr Nehemias Wehl, two nurses and eighteen female patients, were deported from the sanatorium and sent to the East.
After the war, an estimated 100,000 children were born in the French occupation zone to mothers who had relationships with French soldiers. The French government brought these children to France against the will of their mothers. The Nordrach military hospital became a collection centre for these children. The German mothers had to give up all rights and the children were released for adoption after a health test. The children's home was closed in 1949.
The sanatorium was returned to Jewish ownership as part of the restitution programme. In 1952, a son of Baroness Adelheid von Rothschild sold the property to Thaddäus Zajac, who ran the facility as a lung sanatorium and later as a nursing home until 1969.
In 1993, the nursing home was taken over by the "Oberrheinische Kliniken" based in Bad Krozingen. This organisation was taken over by the Berlin-based Median Group in 2012. Until its closure in 2019, almost one hundred people lived in the nursing home, some of whom had been there for several decades. They were residents of Nordrach and took part in village life as much as they could. The residents were accepted and integrated. In the end, the patients were cared for by 35 employees.
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